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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
HGS
All Species:
23.33
Human Site:
Y467
Identified Species:
46.67
UniProt:
O14964
Number Species:
11
Phosphosite Substitution
Charge Score:
-0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O14964
NP_004703.1
777
86192
Y467
L
D
E
R
R
L
Y
Y
E
G
L
Q
D
K
L
Chimpanzee
Pan troglodytes
XP_511742
777
85768
Y467
L
D
E
R
R
L
Y
Y
E
G
L
Q
D
K
L
Rhesus Macaque
Macaca mulatta
XP_001111673
777
86015
Y467
L
D
E
R
R
L
Y
Y
E
G
L
Q
D
K
L
Dog
Lupus familis
XP_540486
782
86005
Y470
L
D
E
R
R
L
Y
Y
E
G
L
Q
D
K
L
Cat
Felis silvestris
Mouse
Mus musculus
Q99LI8
775
85996
Y465
L
D
E
R
R
L
Y
Y
E
G
L
Q
D
K
L
Rat
Rattus norvegicus
Q9JJ50
776
86228
Y466
L
D
E
R
R
L
Y
Y
E
G
L
Q
D
K
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001083588
751
84100
L461
I
R
D
A
R
G
A
L
N
A
L
R
D
E
H
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q960X8
760
85396
H461
L
D
Q
L
R
Q
E
H
V
E
K
L
R
R
I
Honey Bee
Apis mellifera
XP_393989
830
92147
R466
D
A
L
R
E
E
H
R
E
K
L
R
R
Q
A
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783582
784
87687
H463
L
R
Q
M
Q
M
A
H
K
L
E
I
M
R
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
P40343
622
70927
S363
D
S
I
Y
M
F
A
S
L
V
E
K
M
K
S
Red Bread Mold
Neurospora crassa
Q7RZJ2
724
79729
H458
L
S
K
A
Y
G
Q
H
S
I
G
G
Y
N
L
Conservation
Percent
Protein Identity:
100
95.5
98.8
92.3
N.A.
93.3
93.4
N.A.
N.A.
N.A.
80
N.A.
N.A.
41.7
47.7
N.A.
49.4
Protein Similarity:
100
96.6
98.9
94.2
N.A.
95.6
95.6
N.A.
N.A.
N.A.
87.5
N.A.
N.A.
55.7
60.9
N.A.
61.3
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
20
N.A.
N.A.
20
20
N.A.
6.6
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
N.A.
46.6
N.A.
N.A.
46.6
40
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
24.9
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
40.6
41
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
6.6
13.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
13.3
26.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
9
0
17
0
0
25
0
0
9
0
0
0
0
9
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
17
59
9
0
0
0
0
0
0
0
0
0
59
0
0
% D
% Glu:
0
0
50
0
9
9
9
0
59
9
17
0
0
9
0
% E
% Phe:
0
0
0
0
0
9
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
17
0
0
0
50
9
9
0
0
0
% G
% His:
0
0
0
0
0
0
9
25
0
0
0
0
0
0
9
% H
% Ile:
9
0
9
0
0
0
0
0
0
9
0
9
0
0
9
% I
% Lys:
0
0
9
0
0
0
0
0
9
9
9
9
0
59
0
% K
% Leu:
75
0
9
9
0
50
0
9
9
9
67
9
0
0
59
% L
% Met:
0
0
0
9
9
9
0
0
0
0
0
0
17
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
9
0
0
0
0
9
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
17
0
9
9
9
0
0
0
0
50
0
9
0
% Q
% Arg:
0
17
0
59
67
0
0
9
0
0
0
17
17
17
9
% R
% Ser:
0
17
0
0
0
0
0
9
9
0
0
0
0
0
9
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
9
9
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
9
9
0
50
50
0
0
0
0
9
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _